Nitrous Acid Deamination of Methyl Ester Methyl beta-Glycoside of Neuraminic Acid.

Chemoenzymatic synthesis of neuraminic acid containing C-glycoside polymers.

[structure: see text] Two neuraminic acid-based, C-glycoside polymers were synthesized. Preliminary studies on one of these polymers showed potent neuraminidase inhibitory activity, suggesting potential utility as an antipathogenic surface coating for the preparation of antimicrobial biomaterials.

FATTY ACID METHYL ESTER PROFILING OF Enterococcus and E

Synthesis of a serine-based neuraminic acid C-glycoside.

Cell-surface carbohydrates are classified by the nature of their linkages to the protein as either N-linked or O-linked. O- and N-glycans are involved in a number of important biological functions. These activities can be lost on glycoprotein catabolism when these glycan linkages are enzymatically hydrolyzed. The design and synthesis of novel C-linked glycans should provide catabolically stable...

Automated determination of fatty acid methyl ester and cis/trans methyl ester composition of fats and oils.

The determination of the fatty acid composition (as methyl esters, FAMEs) of fats and oils and their cis/trans (CTME) distribution requires a simple, but manual and time-consuming sample preparation. The so-called BF3 method is often the preferred procedure. Because FAME/CTME analyses are encountered very frequently in the food industry, an automated, robot-based alternative is proposed which u...

Colletruncoic Acid Methyl Ester, a Unique Meroterpenoid from Colletotrichum truncatum*

M etabolites isolated from the soybean pathogen Colletotrichum truncatum w ere identified as mesoand d -( —)-butane-2,3-diol and the previously u n rep o rted com pound, colletruncoic acid m ethyl ester, to which structure 1 is assigned m ainly on 'H and 13C M R evidence. T he com pound has a skeleton unpreceden ted for a fungal polyketide. T he previously unknow n 2-hydroxym ethylhexa-2,4-dien...